Imagine a late-night TV host walks into an advertising agency for a comedy bit, completely unaware that his life is about to change forever. That’s exactly what happened back in 1999 when a certain red-haired comedian named Conan O’Brien locked eyes with a sharp-witted woman who would later become his wife.
Their first interaction was pure gold, captured on live television, with him joking that he was falling for her—literally. Fast forward to today, and that spontaneous spark has turned into a decades-long marriage, two brilliant kids, and a family life that somehow stays refreshingly down-to-earth despite the Hollywood glare.
From ‘Late Night’ to Dad Life: How Conan O’Brien Became the Side Character in His Own Family’s Story
The woman who stole his heart is Liza Powel O’Brien, 54, a playwright and storyteller with a quiet but formidable creative streak. She’s not just the wife of a famous funnyman; she’s an artist in her own right, crafting plays that dig into human nature and hosting a podcast that uncovers the hidden figures behind history’s biggest names. While her husband thrives in the spotlight, Liza prefers the background, shaping narratives from behind the scenes. Their dynamic works because they balance each other out—he’s the larger-than-life entertainer, and she’s the steady, thoughtful force keeping things real.
Their wedding in 2002 was a low-key affair by celebrity standards, held in Seattle with close friends and family, including Lisa Kudrow from Friends. No over-the-top theatrics, just genuine love and a few well-timed jokes. That’s been the theme of their relationship ever since: humor mixed with sincerity. They’ve managed to keep their private life just that—private—without the usual tabloid drama. In an industry where marriages often crumble under scrutiny, theirs has held strong, built on mutual respect and a shared sense of humor.

Then came the kids, and everything got even better. Neve, their eldest, arrived in 2003, and from the start, it was clear she was going to be a force. Smart, creative, and unafraid to challenge the status quo, she grew up with a love for history, art, and activism. By the time she hit high school, she was already making waves, lobbying for gun control and diving into music production. Now at Yale, she’s carving her own path, far removed from her dad’s late-night antics, though she still has that same sharp wit. Conan loves bragging about her, even if she rolls her eyes at his dad jokes.
Beckett, their youngest, is the family’s resident tech genius. As a kid, he idolized Steve Jobs so much that he dressed up as him for a school project, earning the nickname “little Steve” from his proud dad. Unlike his sister, Beckett has stayed mostly out of the public eye, with Conan making a conscious effort to give him a normal childhood. No red carpets, no forced interviews—just space to grow up without the weight of fame. Now a high school graduate, Beckett’s future is wide open, but one thing’s for sure: he’s inherited his parents’ curiosity and drive.
What’s striking about them is how normal they’ve kept things. Sure, Conan O’Brien’s job means he’s constantly in the public eye, but at home, he’s just Dad—the guy who embarrasses his children with dad jokes and over-the-top pride. Liza keeps the ship steady, blending her creative work with the rhythms of family life. They don’t do flashy vacations or staged photo ops. Instead, they prioritize real moments, whether it’s Neve dragging Conan to Coachella or Beckett schooling him on the latest tech.
Even after all these years, Conan, 62, still talks about fatherhood with a mix of awe and gratitude. He jokes that his kids find him hopelessly uncool, but you can tell he wouldn’t have it any other way. For a man who built a career on making people laugh, his greatest role has been as a husband and dad. And Liza? She’s the quiet backbone of it all, the one who keeps the laughter grounded in something real. Together, they’ve built a family that’s warm, smart, and just a little bit ridiculous—exactly how it should be.
In a world where celebrity relationships often feel like performance art, theirs is refreshingly genuine. No scandals, no messy headlines, just a love story that began on camera and turned into something even better off-screen. And the best part? It’s still unfolding, one laugh at a time.